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312 Uppsatser om Genetic ontology - Sida 1 av 21

Ett verktyg för konstruktion av ontologier från text

With the growth of information stored over Internet, especially in the biological field, and with discoveries being made daily in this domain, scientists are faced with an overwhelming amount of articles. Reading all published articles is a tedious and time-consuming process. Therefore a way to summarise the information in the articles is needed. A solution is the derivation of an ontology representing the knowledge enclosed in the set of articles and allowing to browse through them. In this thesis we present the tool Ontolo, which allows to build an initial ontology of a domain by inserting a set of articles related to that domain in the system.

Individuation : Ontogenes : Prolegomena till Gilbert Simondons genetiska ontologi

The following text constitutes an attempt to present the French philosopher Gilbert Simondon's Genetic ontology through an account of his reconfiguration of the problem of individuation in his doctoral thesis from 1958, L'individuation à la lumière des notions de forme, information, potentiel, métastabilité. The intention is to show how Simondon through this reconfiguration of a classical philosophical problem ? in which concepts and schemas from contemporary physics and technology is utilised in a critique of the bi-polar hylomorphic schema as its traditional, substantialistic solution ? becomes able to articulate an anti-substantialistic and anti-reductionistic ontogenesis as first philosophy. A systematic philosophical conception that according to Simondon precedes every critical investigation of the subject as well as every scientific ontology ? not by establishing a pre-critical position, but by exceeding Kant's critical position: that is, through a displacement toward a conception of the transcendental conditions for the genesis of being and thought as real conditions, rather than conditions of mere possibility.

Från luddig verklighet till strikt formalism : Utveckling av en metod för den semantiska webben

Internet is the world?s largest source of information, and it is expanding every day. It is possible to find all kind of information as long as you know how and where to look for it, but still it is only the words itself that are searched for. We have with this essay tried to find an approach that makes it possible to give the word a meaning or a context.We have, as a starting point used the Socrates method, which is a method that breaks down texts into its smallest elements and forms activities. We have redone these activities to ontologies by forming general and specific descriptions of the activities.

Genetiska defekter hos nötkreatur :

Genetic defects are caused by mutations in major genes where the gene?s protein product has a large impact on the physiology of the animal. The synthesis of the protein can be altered by a change in the nucleotide sequence, which can lead to malformation and in many cases death.One of the main reasons of increase in many genetic defects is the use of few bulls in breeding programmes, causing a reduction of the genetic variation. Genetic defects cause suffering for the animal and influences the production by, for example, increased costs due to misscarriages, lost milk production and expenditure for medical treatment. Bovine Leukocyte Adhesion Deficiency (BLAD) and Complex Vertebral Malformation (CVM) are two genetic defects that were widespread before the causative mutation was discovered.

Patellar luxation - a genetic study

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Inkarnationens ontologi : En studie av Wolfhart Pannenbergs kristologi i belysning av uppenbarelse som historia

Summary in EnglishThe purpose of this essay has been to examine the Christology of Wolfhart Pannenberg, and especially his interpretation of the belief in Jesus as true God and true man. The consequences for his ontology and his view of the incarnation are also focused upon.Fundamental features in the Christology of Pannenberg demand a closer examination in this connection. First, christological method regarding which a certain development can be shown from the early to the late writings of Pannenberg. According to my view, the later Pannenberg is more balanced in his way of describing the christological movements "from above" and "from below" and how these movements complement each other. In contradistinction to his mature Systematic Theology, in Jesus, God and Man from the 1960s he was more categorically an advocate of the from-below-perspective.Secondly, Pannenberg risks his entire Christology claiming the historicity of the resurrection.

Ontologier i kunskapsorganisation Vägen från tesaur till den semantiska webben

This thesis aims to analyse ontology, primarily as the word is used in the context of the Semantic Web. One of the main questions is how ontologies relate to classification and thesauri, two concepts well known within Library and Information Science. The vision of the Semantic Web, a more intelligent addition to the current World Wide Web, has raised the question of how to deal with information scattered over a multitude of locations, stored in different formats, written in different languages et cetera. This issue is in many ways similar to the classical problems encountered in library science: how to classify and categorise large amounts of information. The use of ontologies is one of the main steps leading to the Semantic Web, as well as a tool which can be used in other areas of information organisation and management.

Population genetic analysis and breed assignment of three Swedish horse breeds

The genetic relationship between three Swedish horse breeds was investigated using microsatellite data from 144 loci in 30 horses. The North Swedish Trotter is believed to have been crossed with the Standardbred in the 1950?s to produce a faster trotter. If true, the North Swedish Trotter should be more alike the Standardbred than what the North Swedish Draught Horse is, from which they originate. This was investigated using F-statistics and Nei?s distance in GENEPOP and GENETIX and cluster assignment in STRUCTURE.

Genetic diversity of Roseroot (Rhodiola rosea L.) from Sweden, Greenland and Faroe Islands

Roseroot (R. rosea L.) has gained more attention the last years, mainly because of its phy-topharmacologic properties. Even though many reports in roseroot have been published, only a few articles are dealt with the genetic diversity. The Nordic Genetic Resource Center has collected Roseroot material from Sweden, Greenland and Faroe Islands under different expeditions. The samples were analysed to study the genetic diversity study.

Genetiska ultraljudsmarkörer : Hur bör information till blivande föräldrar i samband med rutinultraljudet hanteras?

Objective: The purpose of the study is to explore and illustrate how ultrasound midwives and medical specialist in obstetrics and gynecology believe the information given to parents about the genetic soft markers should be handled.Design: A quantitative questionnaire study with cross-sectional design. Participants: 44 ultrasound midwives and 37 medical specialists in obstetrics and gynecology.Findings: Most of the participants would like to inform before the ultrasound starts that they will be looking for genetic softmarkers during the ultrasound. Likewise the majority wanted to inform the parents about possible increases in the risk for chromosomal abnormalities based on findings on the routine ultrasound. There was a difference in frequency between those who responded that they would like to inform before the ultrasound that they will be looking for genetic softmarkers and those who responded that they believe the future parents wants information before the examination.Key conclusions: It could help health care professionals in their role as information providers if there were common recommendations for the information to be given to future parents about genetic softmarkers in connection with the routine ultrasound.

Förvildade husdjur : möjligheter och hot

Feral animal populations are distributed over many parts of the world and are often seen as a problem. Since they are a threat against other species, destroy farmlands and can spread dis-eases, they are often referred to as pests. Artificial selection has contributed to loss of genetic diversity in our domesticated animals. Feral animal populations are affected by natural selec-tion, which allows them to adapt to the environment. Their ability to adapt is a reason to see them as pests but can also be seen as an asset.

International and national genetic evaluation of beef cattle : validation of national genetic evaluation models

After a workshop in Kuopio held in June 2006, Interbull decided to go forward with the development of a system for beef international genetic evaluation and a three year project called Interbeef was launched in June 2007. The participating countries are so far limited to Europe and the only trait evaluated at present is adjusted weaning weight (weight at 200 days). The results from a first international genetic evaluation have been shared with the countries but are not yet official. The evaluation is based on data from purebred Charolais and Limousin. To achieve good estimates of proofs in an international context it is important that methods for data validation and model selection are implemented.

Genetic variation in local Swedish sheep breeds

Sheep have played a very important part in rural history. In Sweden there were many kinds of small native breeds, kept for their meat and fleece. Women cared for the flock that often had very little to feed on during the cold and sometimes harsh winter months. This meant that these sheep over time acquired special phenotypic properties depending on the environment they lived in, and easily fed compared to modern breeds kept for meat. Most of these sheep have since become extinct.

Förekomsten av den genetiska varianten laktapersistens hos neolitiska grupper från Öland : The contribution of the genetic variant Lactase persistence among Neolithic people from the Baltic island Öland in Sweden

This study deals with the contribution of the genetic variant lactase persistence among Neolithic people from the Baltic Island Öland. Skeletal remains from twelve individuals went through DNA sequencing in order to find the mutation that allows adult individuals to digest milk sugar. The twelve individuals were chosen from two different Neolithic sites, where the archaeological and isotopic data suggest that the individuals from Köpingsvik were hunters and gatherers and the individuals from Resmo were early farmers. The individuals with the genetic variant lactase persistence can be described with selection and genetic flow.  Only five individuals produced results and the mutation was found in two of the subjects. All the individuals who were successfully sequenced came from Resmo, whereasno individuals from Köpingsvik yielded any results.

Arvets betydelse för mjölkkors beteende :

It becomes more important to consider different behaviour traits in the selection for dairy cows to be suitable in the production systems of today. The purpose of this investigation was to study the genetic background to behavioural traits and the heritabilities for temperament, rank order, aggressiveness, feeding behaviour and for learning behaviour. Moreover, the genetic correlations to other traits were studied. To be included in a breeding programme a trait needs to have enough genetic variation, a moderate to high heritability or to be correlated to another measurable trait. Behaviour is a quantitative trait affected by many genes and the environment.

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